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Serotypes and antimicrobial resistance of < em > Streptococcus pneumoniae < /em > in children under 5 years of age pre- and post-pneumococcal conjugate vaccine introduction in Paraguay
Conclusion. A change in the circulating serotypes and antimicrobial resistance to certain antibiotics was observed. Non-vaccine serotype circulation and multidrug resistance may compromise the success of the conjugate vaccines.PMID:37289483 | DOI:10.1099/jmm.0.001700
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Mar ía Eugenia León Margarita Samudio An íbal Kawabata Minako Nagai Liliana Rojas Noem í Zárate Juan Irala Myrian Leguizam ón Gloria G ómez Juana Ortellado Raquel Blasco Rossana Franco Gustavo Chamorro Source Type: research

Prevalence, capsular types, antimicrobial resistance and risk factors associated with pneumococcal carriage among children after long-term 10-valent pneumococcal conjugate vaccine use in Brazil
CONCLUSIONS: Long-term universal childhood use of PCV10 has nearly eliminated carriage with PCV10 serotypes, but the high frequency of MDR isolates, especially associated with serotype 6C/D, remains a concern. Replacing PCV10 with PCV13 should reduce the proportion of ERY-R isolates and PNSP by at least 14% and 18%, respectively.PMID:37061371 | DOI:10.1016/j.vaccine.2023.04.023
Source: Vaccine - April 15, 2023 Category: Allergy & Immunology Authors: Let ícia B D P Fortuna Filipe M Miranda Isa M F Antunes Amanda B Silva Amanda S Cabral Ítalo M Dolores Nayara T Cardoso-Marques L úcia M Teixeira Felipe P G Neves Source Type: research

Newborn medication adherence and childhood under-immunization in military beneficiaries
CONCLUSIONS: Refusal of the hepatitis B vaccine in the nursery is associated with a risk of being under-immunized in childhood. Obstetric and pediatric providers should be aware of this association for appropriate family counseling.PMID:37005102 | DOI:10.1016/j.vaccine.2023.03.052
Source: Vaccine - April 2, 2023 Category: Allergy & Immunology Authors: Rasheda J Vereen James K Aden Caitlin M Drumm Source Type: research

Integrated computational approaches assisted development of a novel multi-epitope vaccine against MDR Streptococcus pseudopneumoniae
Braz J Biol. 2023 Feb 13;84:e269313. doi: 10.1590/1519-6984.269313. eCollection 2023.ABSTRACTThe emergence of antibiotic resistance (AR) in bacteria is becoming an alarming health concern because it allows them to adapt themselves to changing environments. It is possible to prevent the spread of AR in many ways, such as reducing antibiotic misuse in human and veterinary medicine. Streptococcus pseudopneumoniae is one of these AR bacterial species that can cause pneumonia in humans and is responsible for high mortality and morbidity rates. It is oval shaped gram-positive bacterium that shows resistance to several antibiotic...
Source: Braz J Biol - February 15, 2023 Category: Biology Authors: R Attar Source Type: research

Carriage prevalence, serotype distribution, antimicrobial resistance, pspA typing and pilus islets of Streptococcus pneumoniae isolated from adults living in a Brazilian urban slum
CONCLUSION: We detected a low frequency of pneumococcal carriage among the adult population, but a high diversity of serotypes. Frequencies of PNSP and NT isolates resistant to antimicrobial agents are concerning.PMID:36690557 | DOI:10.1016/j.vaccine.2023.01.034
Source: Vaccine - January 23, 2023 Category: Allergy & Immunology Authors: Amanda Beiral da Silva Nayara Torres Cardoso-Marques Ítalo de Moraes Dolores L úcia Martins Teixeira Felipe Piedade Gon çalves Neves Source Type: research

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